Heterophile Antibodies to Bovine and Caprine Proteins Causing False-Positive Human Immunodeficiency Virus Type 1 and Other Enzyme-Linked Immunosorbent Assay Results
Abstract
Heterophile Antibodies to Bovine and Caprine Proteins Causing False-Positive Human Immunodeficiency Virus Type 1 and Other Enzyme-Linked Immunosorbent Assay Results Joseph H. Willman , Thomas B. Martins , Troy D. Jaskowski , Harry R. Hill , and Christine M. Litwin * Division of Clinical Pathology, Department of Pathology, and Department of Pediatrics, University of Utah, ARUP Laboratories and the ARUP Institute for Clinical and Experimental Pathology, Salt Lake City, Utah 84132 ABSTRACT Heterophile antibodies are a well-recognized cause of erroneous results in immunoassays. We describe here a 22-month-old child with heterophile antibodies reactive with bovine serum albumin and caprine proteins causing false-positive results to human immunodeficiency virus type 1 and other infectious serology testing.