Evaluation of a Monoclonal Antibody-Based Test for Detection of Helicobacter pylori-Specific Antigen in Stool Samples from Mice
Clinical and Vaccine Immunology
, Volume 11 (4): 799 – Jul 1, 2004
Abstract
A test using monoclonal antibodies for detection of antigen in stool samples was compared with culture and histology for noninfected ( n = 25), Helicobacter pylori -infected ( n = 25), and Helicobacter felis -infected ( n = 6) mice. Sensitivity and specificity were 96%. The monoclonal antibody-based test is therefore a noninvasive technique that is able to diagnose H. pylori infection in mice.
