Elimination of False-Positive Results in a Luminex Assay for Pneumococcal Antibodies
Clinical and Vaccine Immunology
, Volume 17 (1): 185 – Jan 1, 2010
Abstract
In our 14-valent Luminex assay for pneumococcal antibodies, we identified two groups of sera that caused false-positive results. The first group bound nonspecifically to the Luminex microspheres. The second group reacted specifically with bovine serum albumin (BSA). We describe here methods that eliminated the false-positive reactivity of both groups.
