Advances in dengue diagnosis.
Abstract
Receive: RSS Feeds, eTOCs, free email alerts (when new articles cite this article), more» Information about commercial reprint orders: http://cvi.asm.org/site/misc/reprints.xhtml To subscribe to to another ASM Journal go to: http://journals.asm.org/site/subscriptions/ CLINICAL AND DIAGNOSTIC LABORATORY IMMUNOLOGY, Nov. 1996, p. 621â627 1071-412X/96/$04.00 0 Copyright 1996, American Society for Microbiology Vol. 3, No. 6 ´ ´ MARIA G. GUZMAN* AND ´ GUSTAVO KOURI Institute of Tropical Medicine âPedro Kouri,â Havana, Cuba INTRODUCTION Despite improvements in health, epidemics of infectious diseases continue to occur, and new diseases emerge and old diseases reemerge (113). Mosquito-borne ï¬avivirus diseases are currently considered reemerging infections because of the increase in the incidences of yellow fever and, mainly, dengue fever and dengue hemorrhagic fever/dengue shock syndrome (DHF/DSS) observed in the last few years (30, 86). The dengue syndrome is an acute febrile viral exanthem, accompanied by headache, myalgia, anorexia, gastrointestinal disturbances, and postration, caused by viruses transmitted by mosquitoes (43). DHF is a severe febrile disease characterized by abnormalities of hemostasis and increased vascular permeability. DSS is the result of a hypovolemic shock observed in some DHF cases. DHF/DSS represents the severe form of dengue fever (52). The disease is caused by any one of the four