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Antidepressant medication is generally considered the primary treatment formajor depressive disorders (MDD), but antidepressant treatment has recentlyapproached a crisis with shrinking specific effects and growing placeboresponses in current trials. The aim of the paper is to review the placeboproblem within antidepressant treatment for MDD, and to draw lines to similarproblems within the field of psychotherapy. Although clinicians might profitfrom the large placebo response in their treatment of MDD, the small differencesbetween active treatment and placebo groups found in controlled studies shouldbe considered a reminder that there is a need for more efficacious treatmentsfor MDD, medical as well as psychological.
Nordic Psychology – American Psychological Association
Published: Jul 1, 2010
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