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Placebo and Antidepressant Treatment for Major Depression: Is there a Lesson to be Learned for Psychotherapy?

Placebo and Antidepressant Treatment for Major Depression: Is there a Lesson to be Learned for... Antidepressant medication is generally considered the primary treatment formajor depressive disorders (MDD), but antidepressant treatment has recentlyapproached a crisis with shrinking specific effects and growing placeboresponses in current trials. The aim of the paper is to review the placeboproblem within antidepressant treatment for MDD, and to draw lines to similarproblems within the field of psychotherapy. Although clinicians might profitfrom the large placebo response in their treatment of MDD, the small differencesbetween active treatment and placebo groups found in controlled studies shouldbe considered a reminder that there is a need for more efficacious treatmentsfor MDD, medical as well as psychological. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Nordic Psychology American Psychological Association

Placebo and Antidepressant Treatment for Major Depression: Is there a Lesson to be Learned for Psychotherapy?

Nordic Psychology , Volume 62 (2): 20 – Jul 1, 2010

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References (86)

Publisher
American Psychological Association
Copyright
Copyright © 2010 The authors & Nordic Psychology
ISSN
1901-2276
eISSN
1904-0016
DOI
10.1027/1901-2276/a000008
Publisher site
See Article on Publisher Site

Abstract

Antidepressant medication is generally considered the primary treatment formajor depressive disorders (MDD), but antidepressant treatment has recentlyapproached a crisis with shrinking specific effects and growing placeboresponses in current trials. The aim of the paper is to review the placeboproblem within antidepressant treatment for MDD, and to draw lines to similarproblems within the field of psychotherapy. Although clinicians might profitfrom the large placebo response in their treatment of MDD, the small differencesbetween active treatment and placebo groups found in controlled studies shouldbe considered a reminder that there is a need for more efficacious treatmentsfor MDD, medical as well as psychological.

Journal

Nordic PsychologyAmerican Psychological Association

Published: Jul 1, 2010

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