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F. W. Newell (1947)
Stimulation of Corneal Epithelization with Topical Application of Erythrocytes: Experimental StudyAm. J. Ophth., 30
J. F. Cuendet (1954)
Use of Fibrin Films in Treatment of KeratitisOphthalmologica, 127
T. Parry, G. Laszlo (1946)
THROMBIN TECHNIQUE IN OPHTHALMIC SURGERYBritish Journal of Ophthalmology, 30
J. C. Heerema (1950)
Retardation of Wound Healing in Corneal Epithelium by LanolinAm. J. Ophth., 33
A. J. Schaeffer (1944)
Effects of Certain Amino Acids on Healing of Experimental Wounds of CorneaProc. Soc. Exper. Biol. & Med., 61
P. Toulant , A. Larmande (1951)
Instillations of Fresh Blood in Therapy of Burns of CorneaBull. Acad. nat. méd., 135
J. Cuendet, V. Michels (1954)
Le film de fibrine dans le traitement des kératitesOphthalmologica, 127
W. Marr, R. Wood, M. Grieves (1954)
Further studies on the effect of agents on regeneration of corneal epithelium.American journal of ophthalmology, 37 4
C. Weisser (1954)
Fibrin film treatment of corneal diseases.A.M.A. archives of ophthalmology, 51 5
J. P. Rigg (1959)
Corneal HealingAm. J. Ophth., 48
P. Toulant, A. Larmande, M. Toulant (1951)
[Instillation of fresh blood in the treatment of burns of the cornea].Bulletin de l'Academie nationale de medecine, 135 15-16
J. Moorhead, L. Unger (1943)
Human red cell concentrate for surgical dressingsAmerican Journal of Surgery, 59
Abstract One of the most common injuries of the eye is corneal abrasion, a loss of epithelium from Bowman's membrane. Although a small abrasion may heal within 12 hours, a large one may incapacitate the patient for several days because of intense pain, photophobia, and lacrimation. Furthermore, if healing is delayed, secondary infection may lead to ulceration, with permanent scarring and visual impairment. Many chemical and physical agents have been proposed to stimulate wound healing but most have proved to be of little benefit. Of those showing promise, nearly all are biological products or derivatives. Schaeffer (1944) observed an increased rate of corneal epithelization in abraded eyes treated with buffered amino acids. Moorhead (1943) used red cell concentrates for surgical wound dressing, and Newell (1947) used red cell concentrates mixed in ointment base to promote corneal epithelization. Although ointments are soothing to painful, denuded corneas, they delay healing and are suspected References 1. Schaeffer, A. J.: Effects of Certain Amino Acids on Healing of Experimental Wounds of Cornea , Proc. Soc. Exper. Biol. & Med. 61:165, 1944. 2. Moorhead, J. J., and Unger, L. J.: Human Red Cell Concentrates for Surgical Dressings , Am. J. Surg. 59:104, 1943. 3. Newell, F. W.: Stimulation of Corneal Epithelization with Topical Application of Erythrocytes: Experimental Study , Am. J. Ophth. 30:1238-1243, 1947. 4. Heerema, J. C., and Friedenwald, J. S.: Retardation of Wound Healing in Corneal Epithelium by Lanolin , Am. J. Ophth. 33:1421-1427, 1950. 5. Parry, T. G. W., and Laszlo, G. C.: Thrombin Technique in Ophthalmic Surgery , Brit. J. Ophth. 30:176-178, 1946. 6. Toulant, P.; Larmande, A., and Toulant, M.: Instillations of Fresh Blood in Therapy of Burns of Cornea , Bull. Acad. nat. méd. 135:279-281, 1951. 7. Rigg, J. P., and Rigg, R. W.: Corneal Healing , Am. J. Ophth. 48:238-252 (Sept., (Pt. 2) ) 1959. 8. Weisser, C. W.: Fibrin Film Treatment of Corneal Diseases , A.M.A. Arch. Ophth. 51:681, 1954. 9. Cuendet, J. F., and Michels, V.: Use of Fibrin Films in Treatment of Keratitis , Ophthalmologica 127:301, 1954. 10. Marr, W. G.; Wood, R., and Grieves, M.: Further Studies on the Effect of Agents on Regeneration of Corneal Epithelium , Am. J. Ophth. 37:544, 1954.
A.M.A. Archives of Ophthalmology – American Medical Association
Published: Jun 1, 1960
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