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Thyroidal Accumulation of Radioiodine in Children

Thyroidal Accumulation of Radioiodine in Children Abstract Although a large volume of information on the radioiodine uptake by the thyroid of the adult is available, there is relatively little such information concerning the infant and child. For the most part, published data for the child or infant relate to the normal or hypothyroid person and pertain to the period between 24 and 96 hours following the administration of the radioiodine test dose. The present study concerns the thyroid uptake of radioiodine as a function of the status of the thyroid gland, the age of the patient, and the time after the administration of the test dose. It provides data on the effect of the thyroid-stimulating hormone (TSH) on thyroidal accumulation of radioiodine in the euthyroid, the primary hypothyroid, and the pituitary hypothyroid child. In a recent paper by Martmer, Corrigan, Charbeneau, and Sosin,1 the 24-hour radioiodine uptake in 65 premature infants was reported as being within References 1. Martmer, E. E.; Corrigan, K. E.; Charbeneau, H. P., and Sosin, A.: A Study of the Uptake of Iodine (I131) by the Thyroid of Premature Infants , Pediatrics 17:503-509 ( (April) ) 1956. 2. Van Middlesworth, L.: Radioactive Iodide Uptake of Normal Newborn Infants , A. M. A. Am. J. Dis. Child. 88:439-442 ( (Oct.) ) 1954. 3. Quimby, E. H., and McCune, D. J.: Uptake of Radioactive Iodine by the Normal and Disordered Thyroid Gland in Children: A Preliminary Report , Radiology 49:201-205 ( (Aug.) ) 1947.Crossref 4. Reilly, W. A., and Bayer, D. I.: The Value of the Measurements of Thyroid Uptake and Urinary Excretion of I131 in Assessing Thyroid Function of Normal and Congenitally Hypothyroid Children , J. Pediat. 40:714-721 ( (June) ) 1952.Crossref 5. Miller, E. R.; Dailey, M. E.; Holmes, A. V.; Alexander, G. I., and Sheline, G. E.: Studies with Radioiodine: I. Function and Rate of I131 Uptake of the Thyroid , Radiology 57:37-47 ( (July) ) 1951.Crossref 6. Pickering, D. E., and Miller, E. R.: Thyrotropic Hormone in Infants and Children: Differentiation Between Primary and Hypopituitary Hypothyroidism , A. M. A. Am. J. Dis. Child. 85: 135-140 ( (Feb.) ) 1953. 7. Perloff, W. H.; Levy, L. M., and Despopoulos, A.: The Use of Thyrotropic Hormone (TSH) in the Diagnosis of Myxedema , J. Clin. Endocrinol. 11:1495-1502 ( (Dec.) ) 1951.Crossref 8. Bishopric, G. A.; Garrett, N. H., and Nicholson, W. M.: Clinical Value of the TSH Test in the Diagnosis of Thyroid Diseases , Am. J. Med. 18:15-19 ( (Jan.) ) 1955.Crossref http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Journal of Diseases of Children American Medical Association

Thyroidal Accumulation of Radioiodine in Children

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References (10)

Publisher
American Medical Association
Copyright
Copyright © 1957 American Medical Association. All Rights Reserved.
ISSN
0096-6916
DOI
10.1001/archpedi.1957.02060040393006
Publisher site
See Article on Publisher Site

Abstract

Abstract Although a large volume of information on the radioiodine uptake by the thyroid of the adult is available, there is relatively little such information concerning the infant and child. For the most part, published data for the child or infant relate to the normal or hypothyroid person and pertain to the period between 24 and 96 hours following the administration of the radioiodine test dose. The present study concerns the thyroid uptake of radioiodine as a function of the status of the thyroid gland, the age of the patient, and the time after the administration of the test dose. It provides data on the effect of the thyroid-stimulating hormone (TSH) on thyroidal accumulation of radioiodine in the euthyroid, the primary hypothyroid, and the pituitary hypothyroid child. In a recent paper by Martmer, Corrigan, Charbeneau, and Sosin,1 the 24-hour radioiodine uptake in 65 premature infants was reported as being within References 1. Martmer, E. E.; Corrigan, K. E.; Charbeneau, H. P., and Sosin, A.: A Study of the Uptake of Iodine (I131) by the Thyroid of Premature Infants , Pediatrics 17:503-509 ( (April) ) 1956. 2. Van Middlesworth, L.: Radioactive Iodide Uptake of Normal Newborn Infants , A. M. A. Am. J. Dis. Child. 88:439-442 ( (Oct.) ) 1954. 3. Quimby, E. H., and McCune, D. J.: Uptake of Radioactive Iodine by the Normal and Disordered Thyroid Gland in Children: A Preliminary Report , Radiology 49:201-205 ( (Aug.) ) 1947.Crossref 4. Reilly, W. A., and Bayer, D. I.: The Value of the Measurements of Thyroid Uptake and Urinary Excretion of I131 in Assessing Thyroid Function of Normal and Congenitally Hypothyroid Children , J. Pediat. 40:714-721 ( (June) ) 1952.Crossref 5. Miller, E. R.; Dailey, M. E.; Holmes, A. V.; Alexander, G. I., and Sheline, G. E.: Studies with Radioiodine: I. Function and Rate of I131 Uptake of the Thyroid , Radiology 57:37-47 ( (July) ) 1951.Crossref 6. Pickering, D. E., and Miller, E. R.: Thyrotropic Hormone in Infants and Children: Differentiation Between Primary and Hypopituitary Hypothyroidism , A. M. A. Am. J. Dis. Child. 85: 135-140 ( (Feb.) ) 1953. 7. Perloff, W. H.; Levy, L. M., and Despopoulos, A.: The Use of Thyrotropic Hormone (TSH) in the Diagnosis of Myxedema , J. Clin. Endocrinol. 11:1495-1502 ( (Dec.) ) 1951.Crossref 8. Bishopric, G. A.; Garrett, N. H., and Nicholson, W. M.: Clinical Value of the TSH Test in the Diagnosis of Thyroid Diseases , Am. J. Med. 18:15-19 ( (Jan.) ) 1955.Crossref

Journal

A.M.A. Journal of Diseases of ChildrenAmerican Medical Association

Published: Apr 1, 1957

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