Access the full text.
Sign up today, get DeepDyve free for 14 days.
R. A. Ulstrom (1956)
Adrenal Function in Infants and Children?A Symposium
D. H. Nelson (1952)
A Method for the Determining of 17-Hydroxycorticosteroids in Blood: 17-Hydroxycorticosterone in the Peripheral CirculationJ. Clin. Endocrinol., 12
N. Kretchmer (1959)
Enzymatic Patterns During DevelopmentPediatrics, 23
R. Peterson, J. Wyngaarden, S. Guerra, B. Brodie, J. Bunim (1955)
The physiological disposition and metabolic fate of hydrocortisone in man.The Journal of clinical investigation, 34 12
J. Madsen, A. Done, R. Ely, V. Kelley (1959)
Evaluation of water-soluble hemisuccinate esters of hydrocortisone and prednisolone; plasma 17-hydroxycorticosteroid concentrations following intravenous administration.A.M.A. journal of diseases of children, 97 1
R. Cranny, C. Cranny (1958)
The urinary excretion of Porter-Silber chromogens by premature infants.A.M.A. journal of diseases of children, 95 4
R. E. Peterson (1955)
Physiological Disposition and Metabolic Fate of Hydrocortisone in ManAnn. New York Acad. Sc., 61
A. Bongiovanni, W. Eberlein, M. Westphal, T. Boggs (1958)
Prolonged turnover rate of hydrocortisone in the newborn infant.The Journal of clinical endocrinology and metabolism, 18 10
L. T. Samuels , H. Brown, K. Eik-Nes, F. H. Tyler (1957)
Hormones in Blood
E. Collins, A. Forist, E. Nadolski (1956)
Delta1-Hydrocortisone and hydrocortisone: plasma 17-hydroxycorticosteroid concentrations in the dog following oral and intravenous administration.Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine, 93 2
A. Done, R. Ely, L. Olsen, V. Kelley (1955)
The in vivo half-life of exogenous hydrocortisone in patients with rheumatic fever.Metabolism: clinical and experimental, 4 5
N. Kretchmer (1959)
Enzymatic patterns during development; an approach to a biochemical definition of immaturity.Pediatrics, 23 3
Abstract The exact functional status of the adrenal cortex during the newborn period and the limits within which this gland functions during early life are not yet known. Although data are available concerning the urinary excretion of steroids by individual normal premature and term infants,1,2 the correlation between the function of the adrenal cortex, blood levels of adrenal steroids, and tissue utilization and urinary excretion of these hormones remains obscure. It has been generally accepted that the biological half-life of administered hydrocortisone is an indicator of steroid metabolism and it has been shown that the half-life of hydrocortisone is altered in certain diseases, such as rheumatic fever, cirrhosis, and thyrotoxicosis.3,4 The purpose of this communication is to report the results of hydrocortisone half-life studies which were performed on normal newborn infants. Method and Materials Thirteen hydrocortisone half-life determinations were done on 12 patients; 3 patients were "normal" premature infants, References 1. Cranny, R. L., and Cranny, C. L.: The Urinary Excretion of Porter-Silber Chromogens by Premature Infants , A.M.A.J. Dis. Child. 95: 401, 1958. 2. Ulstrom, R. A., and Doeden, D.: Chromatographic Studies of Urinary Steroids in Term and Premature Infants , in Adrenal Function in Infants and Children—A Symposium , edited by L. I. Gardner, New York, Grune & Stratton, Inc., 1956, p. 31. 3. Done, A. K.; Ely, R. S.; Olsen, L. J., and Kelley, V. C.: The in Vivo Half-Life of Exogenous Hydrocortisone in Patients with Rheumatic Fever , Metabolism 4:416, 1955. 4. Peterson, R. E., and Wyngaarden, J. B.: Physiological Disposition and Metabolic Fate of Hydrocortisone in Man , Ann. New York Acad. Sc. 61:297, 1955.Crossref 5. Nelson, D. H., and Samuels, L. T.: A Method for the Determining of 17-Hydroxycorticosteroids in Blood: 17-Hydroxycorticosterone in the Peripheral Circulation , J. Clin. Endocrinol. 12:519, 1952.Crossref 6. Madsen, J. M.; Done, A. K.; Ely, R. S., and Kelley, V. C.: Evaluation of Water-Soluble Hemisuccinate Esters of Hydrocortisone and Prednisolone: Plasma 17-Hydroxycorticosteroid Concentrations Following Intravenous Administration , A.M.A.J. Dis. Child. 97:66, 1959.Crossref 7. Bongiovanni, A. M.; Eberlein, W. R.; Westphal, M., and Boggs, T.: Prolonged Turnover Rate of Hydrocortisone in the Newborn Infant , J. Clin. Endocrinol. 18:1127, 1958.Crossref 8. Samuels, L. T.; Brown, H.; Eik-Nes, K.; Tyler, F. H., and Dominguez, O.: Extra-Adrenal Factors Affecting the Levels of 17-Hydroxycorticosteroids in Plasma , in Ciba Foundation Colloquia, Hormones in Blood , Boston, Little, Brown & Company, 1957, p. 211. 9. Collins, E. J.; Forist, A. A., and Nadolski, E. B.: Δ1-Hydrocortisone and Hydrocortisone: Plasma 17-Hydroxycorticosteroid Concentrations in the Dog Following Oral and Intravenous Administration , Proc. Soc. Exper. Biol. & Med. 93:369, 1956. 10. Kretchmer, N.: Enzymatic Patterns During Development , Pediatrics 23:606, 1959.
A.M.A. Journal of Diseases of Children – American Medical Association
Published: Apr 1, 1960
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.