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L. E. Young (1955)
Hereditary SpherocytosisAm. J. Med., 18
C. Smith, M. Erlandson, I. Schulman, G. Stern (1957)
Hazard of severe infections in splenectomized infants and children.The American journal of medicine, 22 3
R. Gofstein, S. Gellis (1956)
Splenectomy in infancy and childhood; the question of overwhelming infection following operation.A.M.A. journal of diseases of children, 91 6
H. King, H. Shumacker (1952)
SPLENIC STUDIES: I. SUSCEPTIBILITY TO INFECTION AFTER SPLENECTOMY PERFORMED IN INFANCYAnnals of Surgery, 136
M. Bessis (1949)
The use of replacement transfusion in diseases other than hemolytic disease of the newborn.Blood, 4 4
W. J. Kuhns (1953)
Exchange Transfusion in Hemolytic Anemia Complicating Disseminated Lupus ErythematosusA.M.A. Arch. Int. Med., 92
H. Wallerstein (1946)
Treatment of severe erythroblastosis by simultaneous removal and replacement of the blood of the newborn infant.Science, 103 2680
Abstract Hereditary spherocytosis is a congenital hemolytic disease which is characterized by familial transmission, moderate anemia, and decreased red blood cell survival time; red blood cells which demonstrate a spherical configuration and increased mechanical and osmotic fragility; jaundice, splenomegaly, and marked improvement following splenectomy. Despite persistence of the basic defect in the erythrocytes, splenectomy "promptly, completely, and permanently relieves anemia and jaundice in nearly all cases of hereditary spherocytosis."2 Some workers have reported an increased incidence of severe and often fulminating infections following splenectomy in early childhood, suggesting decreased resistance to infection after splenectomy.2,3 One suggests use of more rigid criteria for splenectomy and close postoperative supervision. Another recent article suggests that there is an increased incidence of severe infection in splenectomized persons but that there is no correlation between age at splenectomy and severe sepsis.4 The procedure of exchange transfusion has been used in a variety of References 1. Young, L. E.: Hereditary Spherocytosis , Am. J. Med. 18:486, 1955.Crossref 2. King, H., and Shumacker, H. B., Jr.: Splenic Studies: I. Susceptibility to Infection After Splenectomy Performed in Infancy , Ann. Surg , 136:239, 1952.Crossref 3. Smith, C. H.; Erlandson, M.; Schulman, I., and Stern, G.: Hazard of Severe Infections in Splenectomized Infants and Children , Am. J. Med. 22: 390, 1955.Crossref 4. Gof stein, R., and Gellis, S. S.: Splenectomy in Infancy and Childhood: The Question of Overwhelming Infection Following Operation , A.M.A. J. Dis. Child. 91:566, 1956.Crossref 5. Wallerstein, H.: Treatment of Severe Erythroblastosis by Simultaneous Removal and Replacement of Blood of Newborn Infant , Science 103:583, 1946.Crossref 6. Bessis, M.: The Use of Replacement Transfusion in Diseases Other Than Hemolytic Disease of the Newborn , Blood 4:324, 1949. 7. Kuhns, W. J., and Bauerlein, T. C.: Exchange Transfusion in Hemolytic Anemia Complicating Disseminated Lupus Erythematosus , A.M.A. Arch. Int. Med. 92:284, 1953.Crossref 8. Clinical Conference at St. Christopher's Hospital for Children, Philadelphia, J. Pediat. 44:213, 1954.Crossref 9. Allen, F. H., Jr., and Diamond, L. K.: Erythroblastosis Fetalis , New England J. Med. 257:659-668, 705-712, 761-772, 1957.Crossref
A.M.A. Journal of Diseases of Children – American Medical Association
Published: Feb 1, 1960
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