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ELECTROENCEPHALOGRAPHIC STUDIES OF THE ENCEPHALOPATHIES: 1. Report of a Nonfatal Case of Arsenical Hemorrhagic Encephalopathy with Serial EEG Studies

ELECTROENCEPHALOGRAPHIC STUDIES OF THE ENCEPHALOPATHIES: 1. Report of a Nonfatal Case of... Abstract "HEMORRHAGIC encephalopathy" during arsenical therapy for syphilis was comparatively rare until the advent of rapid treatment methods, several years ago. The incidence of this complication was reviewed by Glaser, Imerman and Imerman,1 who pointed out that the mortality rate in this complication was 76 per cent. Dorothy Russell,2 Scheinker3 and others have noted that the cognomen "hemorrhagic" is really a misnomer and that perivascular necrotic phenomena may be the only notable feature present, rather than the outpouring of red cells. Engel4 and his associates, in their studies on delirium, have emphasized the importance of serial electroencephalograms in the evaluation of the degree of clinical and anatomic recovery. In their investigation of a case of acute arsenical encephalopathy they stressed the degree of change in the electroencephalogram, rather than the appearance of any particular wave frequency. Their method was essentially one of quantitative analysis, in which they References 1. Glaser, M. A.; Imerman, C. P., and Imerman, S. W.: So-Called Hemorrhagic Encephalitis and Myelitis Secondary to Intravenous Arsphenamins , Am. J. M. Sc. 189:64, 1935.Crossref 2. Russell, D. S.: Changes in the Central Nervous System Following Arsphenamine Medication , J. Path. & Bact. 45:357, 1937. 3. Scheinker, I. M.: Genesis of Encephalopathy Due to Arsphenamine (Central Vasoparalysis Due to Arsphenamine) , Arch. Path. 37:91 ( (Feb.) ) 1944. 4. Romano, J., and Engel, G. L.: Delirium: I. Electroencephalographic Data , Arch. Neurol. & Psychiat. 51:356 ( (April) ) 1944. 5. Engel, G. L., and Romano, J.: Delirium: II. Reversibility of the Electroencephalogram with Experimental Procedures , Arch. Neurol. & Psychiat. 51:378 ( (April) ) 1944. 6. Engel, G. L., and Rosenbaum, M.: Delirium: III. Electroencephalographic Changes Associated with Acute Alcoholic Intoxication , Arch. Neurol. & Psychiat. 53:44 ( (Jan.) ) 1945. 7. Engel, G. L.; Romano, J., and Goldman, L.: Delirium: IV. Quantitative Electroencephalographic Study of a Case of Acute Arsenical Encephalopathy , Arch. Neurol. & Psychiat. 56:659 ( (Dec.) ) 1946. 8. Roseman, E.: Electroencephalography of Gunshot Wounds of the Brain, in Surgeon General's History of the War: Head Injuries, to be published. 9. Roseman, E., and Woodhall, B.: Electroencephalogram in War Wounds of the Brain, with Particular Reference to Post-Traumatic Epilepsy , A. Research Nerv. & Ment. Dis., Proc. (1944) 25:200-219, 1946. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Neurology & Psychiatry American Medical Association

ELECTROENCEPHALOGRAPHIC STUDIES OF THE ENCEPHALOPATHIES: 1. Report of a Nonfatal Case of Arsenical Hemorrhagic Encephalopathy with Serial EEG Studies

ROSEMAN, EPHRAIM
Archives of Neurology & Psychiatry , Volume 64 (3) – Sep 1, 1950
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References (11)

Publisher
American Medical Association
Copyright
Copyright © 1950 American Medical Association. All Rights Reserved.
ISSN
0096-6754
DOI
10.1001/archneurpsyc.1950.02310270137009
Publisher site
See Article on Publisher Site

Abstract

Abstract "HEMORRHAGIC encephalopathy" during arsenical therapy for syphilis was comparatively rare until the advent of rapid treatment methods, several years ago. The incidence of this complication was reviewed by Glaser, Imerman and Imerman,1 who pointed out that the mortality rate in this complication was 76 per cent. Dorothy Russell,2 Scheinker3 and others have noted that the cognomen "hemorrhagic" is really a misnomer and that perivascular necrotic phenomena may be the only notable feature present, rather than the outpouring of red cells. Engel4 and his associates, in their studies on delirium, have emphasized the importance of serial electroencephalograms in the evaluation of the degree of clinical and anatomic recovery. In their investigation of a case of acute arsenical encephalopathy they stressed the degree of change in the electroencephalogram, rather than the appearance of any particular wave frequency. Their method was essentially one of quantitative analysis, in which they References 1. Glaser, M. A.; Imerman, C. P., and Imerman, S. W.: So-Called Hemorrhagic Encephalitis and Myelitis Secondary to Intravenous Arsphenamins , Am. J. M. Sc. 189:64, 1935.Crossref 2. Russell, D. S.: Changes in the Central Nervous System Following Arsphenamine Medication , J. Path. & Bact. 45:357, 1937. 3. Scheinker, I. M.: Genesis of Encephalopathy Due to Arsphenamine (Central Vasoparalysis Due to Arsphenamine) , Arch. Path. 37:91 ( (Feb.) ) 1944. 4. Romano, J., and Engel, G. L.: Delirium: I. Electroencephalographic Data , Arch. Neurol. & Psychiat. 51:356 ( (April) ) 1944. 5. Engel, G. L., and Romano, J.: Delirium: II. Reversibility of the Electroencephalogram with Experimental Procedures , Arch. Neurol. & Psychiat. 51:378 ( (April) ) 1944. 6. Engel, G. L., and Rosenbaum, M.: Delirium: III. Electroencephalographic Changes Associated with Acute Alcoholic Intoxication , Arch. Neurol. & Psychiat. 53:44 ( (Jan.) ) 1945. 7. Engel, G. L.; Romano, J., and Goldman, L.: Delirium: IV. Quantitative Electroencephalographic Study of a Case of Acute Arsenical Encephalopathy , Arch. Neurol. & Psychiat. 56:659 ( (Dec.) ) 1946. 8. Roseman, E.: Electroencephalography of Gunshot Wounds of the Brain, in Surgeon General's History of the War: Head Injuries, to be published. 9. Roseman, E., and Woodhall, B.: Electroencephalogram in War Wounds of the Brain, with Particular Reference to Post-Traumatic Epilepsy , A. Research Nerv. & Ment. Dis., Proc. (1944) 25:200-219, 1946.

Journal

Archives of Neurology & Psychiatry – American Medical Association

Published: Sep 1, 1950

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