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J. Wilson, J. Karr (1951)
Effects of irradiation on embryonic development. I. X-rays on the 10th day of gestation in the rat.The American journal of anatomy, 88 1
U. Murakami (1952)
Artificial Induction of Pseudencephaly, Short-Tail, Taillessness, Myelencephalic Blebs and Some Fissure Formations (Phenocopies) of the MouseNagoya J. M. Sc., 15
H. Plough (1952)
RADIATION TOLERANCES AND GENETIC EFFECTS
L. Russell (1957)
Effects of Low Doses of X-Rays on Embryonic Development in the MouseProceedings of the Society for Experimental Biology and Medicine, 95
S. P. Hicks (1953)
Developmental Malformations Produced by RadiationAm. J. Roentgen., 66
U. Murakami (1955)
Experimental Embryologic and Pathologic Study on Malformation of the Central Nervous SystemPathology International, 5
G. D. Snell , E. Bodemann (1934)
Translocation in the House Mouse and Its Effect on DevelopmentJ. Exper. Zoöl., 67
U. Murakami (1955)
Experimental Embryologic and Pathologic Study on Malformation of the Central Nervous SystemActa path. japon., 5
R. L. Brent (1957)
The Indirect Effect of Irradiation on Rat EmbryosA. M. A. J. Dis. Child., 93
Abstract Many investigators have attempted to treat animals during early pregnancy with x-radiation and to examine the effect as manifested by abnormalities in the offspring. Generally the objective has been to clarify factors influencing the development of congenital abnormalities and to ascertain the teratogenic dosages of radiation and compare effects at different developmental stages of embryonic life. Thus, the malformations which have been studied were mostly those that had developed in near-term fetuses or in newly born animals. Where abnormal morphogenesis had occurred early in pregnancy, development had been permitted to go on until the relatively late stages at which animals were killed. Moreover, except for a few investigators, such as Wilson and Karr1 and Hicks,2 most others have concentrated on the morphological nature of congenital anomalies and have not concerned themselves with a systematic study of mechanisms leading to maldevelopment. In particular, the mechanisms leading to maldevelopment References 1. Wilson, J. G., and Karr, J.: Effect of Irradiation on Embryonic Development: I. X-Rays on the 10th Day of Gestation in the Rat , Am. J. Anat. 88:1-33, 1951.Crossref 2. Hicks, S. P.: Developmental Malformations Produced by Radiation , Am. J. Roentgen. 66:272-293, 1953. 3. Murakami, U.: Experimental Embryologic and Pathologic Study on Malformation of the Central Nervous System , Acta path. japon. 5( (Supp.) ):495-513, 1955. 4. Plough, H. H.: Radiation Tolerances and Genetic Effects , Nucleonics 10:16-20, 1952. 5. Russell, L. B.: Effect of Low Doses of X-Rays on Embryonic Development in the Mouse , Proc. Soc. Exper. Biol. & Med. 95:174-178, 1957. 6. Murakami, U.: Artificial Induction of Pseudencephaly, Short-Tail, Taillessness, Myelencephalic Blebs and Some Fissure Formations (Phenocopies) of the Mouse , Nagoya J. M. Sc. 15:185-194, 1952. 7. Snell, G. D.; Bodemann, E., and Hollander, W.: Translocation in the House Mouse and Its Effect on Development , J. Exper. Zoöl. 67:93-104, 1934. 8. Brent, R. L.: The Indirect Effect of Irradiation on Rat Embryos , A. M. A. J. Dis. Child. 93:7-8, 1957.
A.M.A. Journal of Diseases of Children – American Medical Association
Published: Sep 1, 1958
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