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Acute Poisoning with Oil of Wintergreen Treated by Exchange Transfusion

Acute Poisoning with Oil of Wintergreen Treated by Exchange Transfusion Abstract In 1832 six enterprising soldiers sweetened their tea with oil of wintergreen to become the principals in the first case report on methyl salicylate poisoning.1 The history of recurrent poisoning with methyl salicylate since that time has been the result of the average family's inability to comprehend the toxic potential of this drug. Lucrezia Borgia might well have conceived the cruel trick of disguising one of the most lethal of household poisons with a sweet, candy-like aroma especially enticing to children. It is amazing to consider that a liquid so noxious that a single teaspoonful has been reported fatal to two adults and three infants2-6 has been used with such careless abandon. It has been used by college boys in the roaring twenties to spike ginger ale,2 swigged by topers looking for something stronger than blended bourbon,7 and swallowed by countless children in the belief that References 1. Beck, T. R., and Beck, J. B.: Elements of Medical Jurisprudence , Philadelphia, J. B. Lippincott Company, 1832. 2. Stevenson, C. S.: Oil of Wintergreen Poisoning , Am. J. M. Sc. 193:772, 1937.Crossref 3. Van Wagenen, H. J., cited by Stevenson, C. S.2 4. Price, J. W., and L'Engle, E. M.: A Fatal Case of Poisoning with Oil of Gaultheria , Am. J. M. Sc. 127:265, 1904.Crossref 5. Hughes, R. F.: A Case of Methyl Salicylate Poisoning , Canad. M. A. J. 27:417, 1932. 6. Howard, C. D.: Accidental Poisoning with Oil of Wintergreen , Boston M. & S. J. 190:978, 1924. 7. Pincoffs, M. C., and Chambers, E. T.: Two Cases of Fatal Oil of Wintergreen Poisoning, Bull. School Med. Univ. Maryland 17:57, 1932. 8. Vleurinck, H., and Bourguignon, D., cited by Stevenson.2 9. MacCready, R. A.: Methyl Salicylate Poisoning: A Report of 5 Cases , New England J. Med. 228:155, 1943. 10. Gross, M., and Greenberg, L. A.: The Salicylates: A Critical Bibliographic Review, New Haven , Conn. Hillhouse Press, 1948. 11. Singer, R. B.: The Acid-Base Disturbances in Salicylate Intoxication , Medicine 33:1, 1954. 12. Kane, T. E.: Oil of Wintergreen Poisoning , J. Iowa M. Soc. 23:238, 1938. 13. Riley, H. D., and Worley, L.: Salicylate Intoxication , Pediatrics 18:578, 1956. 14. De Cortes, A., et al.: L'Exsanguino-transfusion , Rev. méd. Liege 9:421, 1954. 15. Biggs, R. T., and Anrode, H. G.: Boric Acid Poisoning Treated by Exchange Transfusion , Pediatrics 16:109, 1955. 16. Katz, B. E., and Carver, M. W.: Acute Poisoning with Isoniazid Treated by Exchange Transfusion , Pediatrics 18:72, 1956. 17. Done, A. K., and Otterness, B. A.: Exchange Transfusion in the Treatment of Oil of Wintergreen Poisoning , Pediatrics 18:80, 1956. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png A.M.A. Journal of Diseases of Children American Medical Association

Acute Poisoning with Oil of Wintergreen Treated by Exchange Transfusion

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Publisher
American Medical Association
Copyright
Copyright © 1958 American Medical Association. All Rights Reserved.
ISSN
0096-6916
DOI
10.1001/archpedi.1958.02060050311014
Publisher site
See Article on Publisher Site

Abstract

Abstract In 1832 six enterprising soldiers sweetened their tea with oil of wintergreen to become the principals in the first case report on methyl salicylate poisoning.1 The history of recurrent poisoning with methyl salicylate since that time has been the result of the average family's inability to comprehend the toxic potential of this drug. Lucrezia Borgia might well have conceived the cruel trick of disguising one of the most lethal of household poisons with a sweet, candy-like aroma especially enticing to children. It is amazing to consider that a liquid so noxious that a single teaspoonful has been reported fatal to two adults and three infants2-6 has been used with such careless abandon. It has been used by college boys in the roaring twenties to spike ginger ale,2 swigged by topers looking for something stronger than blended bourbon,7 and swallowed by countless children in the belief that References 1. Beck, T. R., and Beck, J. B.: Elements of Medical Jurisprudence , Philadelphia, J. B. Lippincott Company, 1832. 2. Stevenson, C. S.: Oil of Wintergreen Poisoning , Am. J. M. Sc. 193:772, 1937.Crossref 3. Van Wagenen, H. J., cited by Stevenson, C. S.2 4. Price, J. W., and L'Engle, E. M.: A Fatal Case of Poisoning with Oil of Gaultheria , Am. J. M. Sc. 127:265, 1904.Crossref 5. Hughes, R. F.: A Case of Methyl Salicylate Poisoning , Canad. M. A. J. 27:417, 1932. 6. Howard, C. D.: Accidental Poisoning with Oil of Wintergreen , Boston M. & S. J. 190:978, 1924. 7. Pincoffs, M. C., and Chambers, E. T.: Two Cases of Fatal Oil of Wintergreen Poisoning, Bull. School Med. Univ. Maryland 17:57, 1932. 8. Vleurinck, H., and Bourguignon, D., cited by Stevenson.2 9. MacCready, R. A.: Methyl Salicylate Poisoning: A Report of 5 Cases , New England J. Med. 228:155, 1943. 10. Gross, M., and Greenberg, L. A.: The Salicylates: A Critical Bibliographic Review, New Haven , Conn. Hillhouse Press, 1948. 11. Singer, R. B.: The Acid-Base Disturbances in Salicylate Intoxication , Medicine 33:1, 1954. 12. Kane, T. E.: Oil of Wintergreen Poisoning , J. Iowa M. Soc. 23:238, 1938. 13. Riley, H. D., and Worley, L.: Salicylate Intoxication , Pediatrics 18:578, 1956. 14. De Cortes, A., et al.: L'Exsanguino-transfusion , Rev. méd. Liege 9:421, 1954. 15. Biggs, R. T., and Anrode, H. G.: Boric Acid Poisoning Treated by Exchange Transfusion , Pediatrics 16:109, 1955. 16. Katz, B. E., and Carver, M. W.: Acute Poisoning with Isoniazid Treated by Exchange Transfusion , Pediatrics 18:72, 1956. 17. Done, A. K., and Otterness, B. A.: Exchange Transfusion in the Treatment of Oil of Wintergreen Poisoning , Pediatrics 18:80, 1956.

Journal

A.M.A. Journal of Diseases of ChildrenAmerican Medical Association

Published: Mar 1, 1958

References