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D. Hsia, H. Hsia, S. Gellis (1952)
A micromethod for serum bilirubin.The Journal of laboratory and clinical medicine, 40 4
L. Davidson, K. Merritt, A. Weech (1941)
HYPERBILIRUBINEMIA IN THE NEWBORNJAMA Pediatrics, 61
H. Malloy, K. Evelyn (1937)
THE DETERMINATION OF BILIRUBIN WITH THE PHOTOELECTRIC COLORIMETERJournal of Biological Chemistry, 119
A. Weech, D. Vann, R. Grillo (1941)
THE CLEARANCE OF BILIRUBIN FROM THE PLASMA. A MEASURE OF THE EXCRETING POWER OF THE LIVER.The Journal of clinical investigation, 20 3
L. T. Davidson , K. K. Merritt (1941)
Hyperbilirubinemia in the NewbornAm. J. Child., 61
Z. Ernst (1924)
Colorimetric Test for Bilirubin in BloodKlin. Wchnschr., 3
V. Najjar, B. Childs (1953)
The crystallization and properties of serum bilirubin.The Journal of biological chemistry, 204 1
W. C. Stoner (1928)
CarotinemiaAm. J. M. Sc., 175
Abstract Since the indictment of bilirubin as an etiologic factor in the development of kern-icterus, widespread attention has been focused upon neonatal jaundice. Frequent bilirubin determinations are now being done on small infants, and a micromethod that obviates the necessity for venipunctures and at the same time can be easily performed would seem desirable. Because the bilirubin producing icterus in the first week of life, associated with erythroblastosis, sepsis, or prematurity, is almost entirely indirect-reacting, a simple method for determination of indirect bilirubin alone should be of practical value. Such a method, based on that originally described by Ernst and Förster1 and modified by Weech and co-workers * in 1941, is now in use at the Children's Hospital. The addition of acetone to serum precipitates direct bilirubin together with protein and leaves indirect bilirubin in the clear yellow supernate, where its concentration can be determined photometrically. As described by Davidson, Merritt, References 1. Ernst, Z., and Förster, J.: Colorimetric Test for Bilirubin in Blood , Klin. Wchnschr. 3: 2386 ( (Dec.) ) 1924.Crossref 2. Weech, A. A.; Vann, D., and Grillo, R. A.: Clearance of Bilirubin from the Plasma: Measure of the Excreting Power of the Liver , J. Clin. Invest. 20:323 ( (May) ) 1941.Crossref 3. Davidson, L. T.; Merritt, K. K., and Weech, A. A.: Hyperbilirubinemia in the Newborn , Am. J. Child. 61:958 ( (May) ) 1941. 4. Malloy, H. T., and Evelyn, K. A.: Determiation of Bilirubin with the Photoelectric Colorimeter , J. Biol. Chem. 119:481 ( (July) ) 1937. 5. Najjar, V. A., and Childs, B.: Crystallization and Properties of Serum Bilirubin , J. Biol. Chem. 204:359 ( (Sept.) ) 1953. 6. Stoner, W. C.: Carotinemia , Am. J. M. Sc. 175:31 ( (Jan.) ) 1928.Crossref 7. Hsia, D. Y. Y.; Hsia, H. H., and Gellis, S. S.: Micromethod for Serum Bilirubin , J. Lab. & Clin. Med. 40:610 ( (Oct.) ) 1952.
A.M.A. Journal of Diseases of Children – American Medical Association
Published: Jan 1, 1956
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