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Transcranial Magnetic Stimulation (TMS) in Treatment Resistant Depression (TRD): The First Quarter Century

Transcranial Magnetic Stimulation (TMS) in Treatment Resistant Depression (TRD): The First... Over the last quarter century, transcranial magnetic stimulation (TMS) has been researched and applied in clinical practice in the treatment of major depressive disorder (MDD). More than 100 placebo-controlled studies and 20 metaanalyses have shown this treatment to be effective in treatment resistant depression (TRD). This revolutionary modality uses electromagnetism to therapeutically impact brain cortex; it causes few side effects. TMS corrects abnormalities in brain connectivity, and such corrections correlate with changes in mood. TMS is complimentary and not a replacement for electroconvulsive therapy (ECT), a comprehensive service will provide both techniques. The efficacy of TMS is expected to increase with new stimulation protocols. Currently used as a second line treatment, TMS is likely to become a first line option. Currently, expertise is limited to those working in particular clinics – there is a need/call for training to be more widely available. Keywords: connectivity; electroconvulsive therapy; major depressive disorder; treatment resistant depression; transcranial magnetic stimulation http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png American Journal of Medical Research Addleton Academic Publishers

Transcranial Magnetic Stimulation (TMS) in Treatment Resistant Depression (TRD): The First Quarter Century

American Journal of Medical Research , Volume 8 (1): 11 – Jan 1, 2021

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Publisher
Addleton Academic Publishers
Copyright
© 2009 Addleton Academic Publishers
ISSN
2334-4814
eISSN
2376-4481
Publisher site
See Article on Publisher Site

Abstract

Over the last quarter century, transcranial magnetic stimulation (TMS) has been researched and applied in clinical practice in the treatment of major depressive disorder (MDD). More than 100 placebo-controlled studies and 20 metaanalyses have shown this treatment to be effective in treatment resistant depression (TRD). This revolutionary modality uses electromagnetism to therapeutically impact brain cortex; it causes few side effects. TMS corrects abnormalities in brain connectivity, and such corrections correlate with changes in mood. TMS is complimentary and not a replacement for electroconvulsive therapy (ECT), a comprehensive service will provide both techniques. The efficacy of TMS is expected to increase with new stimulation protocols. Currently used as a second line treatment, TMS is likely to become a first line option. Currently, expertise is limited to those working in particular clinics – there is a need/call for training to be more widely available. Keywords: connectivity; electroconvulsive therapy; major depressive disorder; treatment resistant depression; transcranial magnetic stimulation

Journal

American Journal of Medical ResearchAddleton Academic Publishers

Published: Jan 1, 2021

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