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We have seen hydronephrosis (obstructive nephropathy) at necropsy in 3 of 11 (21%) genetically‐engineered pig kidneys that functioned in baboons for >36 days, even when the clinical and histopathological features of rejection were minimal. We briefly report one such case and illustrate the...
The phenomenon of diminishing hematocrit after in vivo liver and lung xenotransplantation and during ex vivo liver xenoperfusion has largely been attributed to action by resident liver porcine macrophages, which bind and destroy human erythrocytes. Porcine sialoadhesin (siglec‐1) was implicated...
Experience from human renal allotransplantation informs us that disturbances in serum calcium and phosphate levels are relatively common. Post‐transplant hypercalcemia is associated with an increased risk of recipient mortality, but not of graft loss or nephropathy, and post‐transplant...
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