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Xenotransplantation could resolve the increasing discrepancy between the availability of deceased human donor organs and the demand for transplantation. Most advances in this field have resulted from the introduction of genetically engineered pigs, e.g., α1,3‐galactosyltransferase gene‐knockout...
Type I diabetes remains a significant clinical problem in need of a reliable, generally applicable solution. Both whole organ pancreas and islet allotransplantation have been shown to grant patients insulin independence, but organ availability has restricted these procedures to an exceptionally...
Baboons have natural antibodies against pig antigens. We have investigated whether there are differences in anti‐non‐Gal pig antibody levels between baboons maintained under specific pathogen‐free (SPF) conditions and those housed under conventional conditions (non‐SPF) that might be associated...
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