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Clinical applications of various blood‐contacting biomaterials have been limited by the complications associated with hemolysis and coagulation on material surfaces. We have been developing anticoagulant‐free polymeric mechanical heart valves with an expanded polytetrafluoroethylene (ePTFE)...
Uperin 3.5 is a short antimicrobial peptide consisting of 17 Amino acids (GVGDL5IRKAV10SVIKN15IV‐NH2) and is naturally obtained from the skin secretion of Uperoleia mjobergii. It is unusual, as it does not aggregate in pure water, but self‐aggregates to form amyloid fibrils in saline buffer....
Overuse of conventional antibiotics as well as the slow pace of new antibiotic drug development leads to antimicrobial resistance (AMR). Because infections with multi‐drug resistant (MDR) pathogens have become a public health issue, the need for a novel class of antibiotics is urgent. Recently,...
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