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Molecular Genetics Microbiology and Virology Volume 27 Issue 1

Subject Areas: Genetics; ; ; ; ; ;
Publisher: Allerton Press, Inc. - Springer Journals
ISSN: 0891-4168
SJR: 10

LitStream

Journal Article

Pseudomonas aeruginosa: Characteristics of the biofilm process

Mayansky, A.; Chebotar, I.; Rudneva, E.; Chistyakova, V.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S0891416812010053

In this review, we define the biofilm process as a type of intercellular bacterial communication. We present up-to-date data on the structure of the Pseudomonas aeruginosa biofilm matrix and genetic mechanisms regulating its formation, discuss processes involved in active or passive rejection of...
LitStream

Journal Article

Oncolytic poxviruses

Kochneva, G. V.; Sivolobova, G. F.; Yudina, K. V.; Babkin, I. V.; Chumakov, P. M.; Netesov, S. V.

2012 "Molecular Genetics, Microbiology and Virology"

doi:10.3103/s0891416812010041

Modern data on selection and design of poxviruses, which are able to specifically lyse tumor cells of various origins and induce antitumor immunity and apoptosis of malignant cells, are presented in this review. Work is being carried out in several areas, including attenuation of viruses,...
LitStream

Journal Article

Oncolytic poxviruses

Kochneva, G.; Sivolobova, G.; Yudina, K.; Babkin, I.; Chumakov, P.; Netesov, S.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S0891416812010041

Modern data on selection and design of poxviruses, which are able to specifically lyse tumor cells of various origins and induce antitumor immunity and apoptosis of malignant cells, are presented in this review. Work is being carried out in several areas, including attenuation of viruses,...
LitStream

Journal Article

Preparation of mycobacterial antigens fused with a cellulose-binding domain with the aim of developing a subunit antituberculous vaccine

Sergienko, O.; Aksenova, E.; Lyashchuk, A.; Galushkina, Z.; Poletaeva, N.; Sharapova, N.; Semikhin, A.; Kotnova, A.; Veselov, A.; Bashkirov, V.; Kulikova, N.; Khlebnikov, V.; Kondrat’eva, T.; Karyagina, A.; Apt, A.; Lunin, V.; Gintsburg, A.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S0891416812010065

The genes of ESAT-6, CFP-10 and Ag85A secreted antigens of Mycobacterium tuberculosis were cloned in Escherichia coli. Fusion proteins Esat6-CBD, Ag85A-CBD and CFP10-CBD with thermostable cellulose binding domain (CBD) of Anaerocellum thermophilum providing high affinity to cellulose were...
LitStream

Journal Article

The Influence of biotinylation of 2F5 antibody on peptide selection from the combinatorial phage library

Shcherbakova, N.; Chikaev, A.; Karpenko, L.; Il’ichev, A.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S0891416812010077

The effect of biotinylation of monoclonal antibodies (MAbs) on the yield and repertoire of peptides selected by biopanning is discussed in the present study. A comparative analysis of peptides selected from a phage library using the biotinylated and nonbiotinylated MAb 2F5 was performed. The...
LitStream

Journal Article

Induction of NO synthesis in lactobacilli under stress conditions

Smolentseva, O.; Yarullina, D.; Ilinskaya, O.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S0891416812010089

It is shown that activation of nitric oxide (NO) biosynthesis in Lactobacillus plantarum 8P-A3 cells takes place under strong stress, which leads to a considerable decrease in the bacterial cell viability. Such stress conditions are heating up to 70 or 80°C, prolonged cultivation, and the toxic...
LitStream

Journal Article

Genetic characterization of wild leguminous nodular bacteria living in the South Urals

Baimiev, An.; Ivanova, E.; Ptitsyn, K.; Belimov, A.; Safronova, V.; Baimiev, Al.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S0891416812010028

The genetic diversity and phylogeny of rhizobia from eight genera belonging to four tribes (Loteae, Genisteae, Galegeae, and Hedysareae) that nodulate 18 species of South Urals wild-growing bean plants are studied. It is demonstrated that symbiotic interaction with various strains of nodule...
LitStream

Journal Article

Novel M.BstC8I methyltransferase forms 5′-G(m5C)NNGC-3′. Investigation of restriction endonuclease sensitivity to M.BstC8I methylation

Dedkov, V.

2012 Molecular Genetics, Microbiology and Virology

doi:10.3103/S089141681201003X

A novel M.BstC8I DNA methylase was detected in cell lysate of Bacillus stearothermophilus C8 grown on Luria agar at 37°C. DNA methylation of bacteriophages λ and T7 in the 5′-G(m5C)NNGC-3′ segment blocked the activity of the BstC8I restrictase. The specificity of the M.BstC8I was analyzed on...

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