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BACKGROUND: CD20-based targeting of B-cells in hematologicmalignancies and autoimmune disorders is associated with outstandingclinical outcomes. Isolation and characterization of VH and VL cDNAsencoding the variable regions of the heavy and light chains of monoclonalantibodies (MAb) is necessary...
AIM: CD44s antigens have been suggested as an efficient biomarker for cancer stemcells. Current study aimed to develop a hybridoma that producing a highaffinity murine anti-human CD44 monoclonal antibody for early diagnosticlaboratory tests of some cancer.MATERIALS AND METHODS: To make hybridoma...
BACKGROUND: Multiple sclerosis (MS) as an auto-immune disease is aninflammatory, demyelinating disease of the central nervous system. Certaingenes have shown to be involved in the initiation of MS but the specificrole of some of them, e.g. IFNAR1 has not been identified in certain...
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