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Diabetology and Metabolic Syndrome

Subject Areas: Endocrinology, Diabetes and Metabolism;
Publisher: BioMed Central - Springer Journals
SJR: 55

Open Access

Journal Article

Pharmacotherapy for obesity: moving towards efficacy improvement

Coutinho, Walmir; Halpern, Bruno

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-023-01233-4 pmid:38172940

Obesity is a chronic, recurring, progressive disease and a major public health problem associated with several other diseases that lead to disability, morbidity, and mortality. The prevalence of obesity has increased at pandemic levels, along with increasing weight-related comorbidities and...
Open Access

Journal Article

A higher TyG index level is more likely to have enhanced incidence of T2DM and HTN comorbidity in elderly Chinese people: a prospective observational study from the reaction study

Su, Wanlu; Wang, Jie; Chen, Kang; Yan, Wenhua; Gao, Zhengnan; Tang, Xulei; Wan, Qin; Luo, Zuojie; Ning, Guang; Mu, Yiming

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01258-3 pmid:38287450

BackgroundTriglyceride glucose index (TyG index) was related with both type 2 diabetes (T2DM) and hypertension (HTN). Prospective studies linking the TyG index to the incidence of T2DM and HTN comorbidity remain unclear. This study aimed to to explore the longitudinal association between TyG and...
Open Access

Journal Article

Correlation between time in range and serum uric acid in Chinese patients with type-2 diabetes: an observational cross-sectional study

Liu, Yan; Peng, Xiaoren; Qiu, Chunjian; Shao, Jiaqing

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01313-z pmid:38509610

BackgroundAt present, the relationship between serum uric acid and blood glucose is controversial, and even opposite conclusions have been reached. We aimed to investigate the relationship between time in range and serum uric acid and estimate the influence of serum uric acid on blood glucose...
Open Access

Journal Article

Exosomes derived from BMSCs enhance diabetic wound healing through circ-Snhg11 delivery

Tang, Tao; Chen, Linyi; Zhang, Ming; Wang, Chuang; Du, Xiaolong; Ye, Shenglin; Li, Xiaoqiang; Chen, Hong; Hu, Nan

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-023-01210-x pmid:38326928

BackgroundExosomes (Exos) generated from bone mesenchymal stem cells (BMSCs) are elucidated to enhance cutaneous wound healing in mice models of diabetes mellitus (DM). While underlying mechanisms remain unknown.MethodsNext-generation sequencing (NGS) was used to examine changes in circRNA...
Open Access

Journal Article

Lipid-lowering drugs and inflammatory bowel disease’s risk: a drug-target Mendelian randomization study

Zhao, Jiaxi; Chen, Rong; Luo, Mengqi; Gong, Hongping; Li, Kaixin; Zhao, Qian

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-023-01252-1 pmid:38191425

BackgroundInflammatory bowel disease (IBD) has been associated with lipid-lowering drugs in observational studies. Drug-target Mendelian randomization (MR) was utilized in this study to examine the causal relationship between lipid-lowering drugs and incidence of IBD, aiming to identify new...
Open Access

Journal Article

Distinct changes to pancreatic volume rather than pancreatic autoantibody positivity: insights into immune checkpoint inhibitors induced diabetes mellitus

Wei, Hung-Hui; Lai, Ying-Chieh; Lin, Gigin; Lin, Cheng-Wei; Chang, Ya-Chu; Chang, John Wen-Cheng; Liou, Miaw-Jene; Chen, I-Wen

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01263-6 pmid:38254155

BackgroundImmune checkpoint inhibitors (ICI) are promising treatment options for various cancers. However, their use is associated with immune-related adverse events (irAEs), including ICI-induced diabetes mellitus (ICI-DM). This study aimed to investigate the clinical features of ICI-DM, with a...
Open Access

Journal Article

Association between stress hyperglycemia ratio and diabetes mellitus mortality in American adults: a retrospective cohort study and predictive model establishment based on machine learning algorithms (NHANES 2009–2018)

Yan, Fengjuan; Zhao, Limin; Quan, Xiaoqing; Zhu, Jialiang

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01324-w pmid:38566220

BackgroundStress hyperglycemia is a physiological response of the body under stress to make adaptive adjustments in response to changes in the internal environment. The stress hyperglycemia ratio (SHR) is a new indicator after adjusting the basal blood glucose level of the population. Previous...
Open Access

Journal Article

Efficacy and safety of once-weekly insulin icodec compared to once-daily insulin g U-100 in patients with type II diabetes: a systematic review and meta-analysis

Saleem, Syed Zia; Fareed, Areeba; Akhtar, Syed Muhammad Muneeb; Farhat, Solay; Taha, Amira Mohamed; Akilimali, Aymar

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01305-z pmid:38566252

Background//ObjectiveDiabetes affects millions of people globally, despite treatment options, adherence and other factors pose obstacles. Once-weekly Insulin Icodec, a novel basal Insulin analog with a week-long half-life, offers potential benefits, enhancing convenience, adherence, and quality...
Open Access

Journal Article

Correction: 2024 UPDATE: the Brazilian Diabetes Society position on the management of metabolic dysfunction‑associated steatotic liver disease (MASLD) in people with prediabetes or type 2 diabetes

Godoy‑Matos, Amélio F.; Valério, Cynthia Melissa; Silva Júnior, Wellington S.; de Araujo‑Neto, João Marcello; Bertoluci, Marcello Casaccia

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01286-z pmid:38419114
Open Access

Journal Article

Prevalence of autoimmune diseases in an admixed population of patients with type 1 diabetes: a multicenter study in Brazil

Gomes, Marilia Brito; Braga, Fernanda Oliveira; Drummond, Karla Guerra; Pinheiro, André; Leal, Franz; Porto, Luís Cristóvão; Ferreira, Livia Leite; Pinheiro, Geraldo da Rocha Castelar; Negrato, Carlos Antonio

2024 Diabetology & Metabolic Syndrome

doi:10.1186/s13098-024-01274-3 pmid:38297335

Background/objectivesThe primary aim of this study was to evaluate the prevalence of autoimmune diseases (AIDs) and its associated factors in an admixed Brazilian population of patients with type 1 diabetes (T1D). The secondary one was to determine the relationship between AIDs and the occurrence...

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