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Behavioural Pharmacology

Subject Areas: Psychiatry and Mental Health; ;
Publisher: Lippincott Williams & Wilkins - Wolters Kluwer Health
ISSN: 1473-5849
SJR: 83

LitStream

Journal Article

Additive effect of histamine and muscimol upon induction of antinociceptive and antidepressant effects in mice

Baghani, Matin; Fathalizade, Farzan; Khakpai, Fatemeh; Fazli-Tabaei, Soheila; Zarrindast, Mohammad-Reza

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000729 pmid:37401392

We investigated the effects of histamine and GABAA receptor agents on pain and depression-like behaviors and their interaction using a tail-flick test and the forced swimming test (FST) in male mice. Our data revealed that intraperitoneal administration of muscimol (0.12 and 0.25 mg/kg)...
LitStream

Journal Article

Exogenous histamine and H2 receptor activation and H3 receptor inhibition in nucleus accumbens modulate formalin-induced orofacial nociception through opioid receptors

Notaj, Azam; Erfanparast, Amir; Tamaddonfard, Esmaeal; Soltanalinejad-Taghiabad, Farhad

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000746 pmid:37578392

It has been demonstrated that the nucleus accumbens (NAc) plays an important role in modulation of nociception due to its extensive connections with different regions of the brain. In addition, this nucleus receives histaminergic projections from tuberomammillary nucleus. Considering the role of...
LitStream

Journal Article

Positive modulation of α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors differentially alters spatial learning and memory in juvenile rats younger and older than three weeks

Mill, Nicholas R.; Ogoe, Richard H.; Valibeigi, Nazanin; Chen, Diyi; Kimbal, Carmen L.; Yoon, Stanley J.; Ganju, Shaunak; Perdomo, Josue A.; Sardana, Anjali; McHail, Daniel G.; Gonzalez, Diego A.; Dumas, Theodore C.

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000764 pmid:38451022

Remarkable performance improvements occur at the end of the third postnatal week in rodents tested in various tasks that require navigation according to spatial context. While alterations in hippocampal function at least partially subserve this cognitive advancement, physiological explanations...
LitStream

Journal Article

Intra-accumbal orexinergic system contributes to the stress-induced antinociceptive behaviors in the animal model of acute pain in rats

Nikoohemmat, Mohammad; Farmani, Danial; Moteshakereh, Seyed Mohammadmisagh; Salehi, Sakineh; Rezaee, Laleh; Haghparast, Abbas

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000763 pmid:38055726

Stress and pain are interleaved at numerous levels - influencing each other. Stress can increase the nociception threshold in animals, long-known as stress-induced analgesia (SIA). Orexin is known as a neuropeptide that modulates pain. The effect of stress on the mesolimbic system in the...
LitStream

Journal Article

Contribution of the intra-hippocampal orexin system in the regulation of restraint stress response to pain-related behaviors in the formalin test

Sadeghi, Mehdi; Zareie, Fatemeh; Gholami, Masoumeh; Nazari-Serenjeh, Farzaneh; Ghalandari-Shamami, Mohadeseh; Haghparast, Abbas

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000755 pmid:37934654

Stress-induced antinociception (SIA) is due to the activation of several neural pathways and neurotransmitters that often suppress pain perception. Studies have shown that the orexin neuropeptide system is essential in pain modulation. Therefore, this study aimed to investigate the role of...
LitStream

Journal Article

Opioid receptor antagonists reduce motivated wheel-running behavior in mice

Kitanaka, Nobue; Arai, Kanayo; Takehara, Kaoko; Hall, F. Scott; Tomita, Kazuo; Igarashi, Kento; Sato, Tomoaki; Uhl, George R.; Kitanaka, Junichi

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000769 pmid:38451023

We hypothesized that opioid receptor antagonists would inhibit motivated behavior produced by a natural reward. To evaluate motivated responses to a natural reward, mice were given access to running wheels for 71.5 h in a multi-configuration testing apparatus. In addition to a running wheel...
LitStream

Journal Article

Antinociceptive and adverse effects of morphine:ketamine mixtures in rats

Strumberger, Conor D.; D’Epagnier, Evangeline J.; Nguyen, Kevin H.; Rogers, John D.; Meyer, Matthew P.; Malhotra, Yashmita; Hinman, Jillian E.; Jansen, Elisabeth L.; Minervini, Vanessa

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000761 pmid:38451024

Prescription opioids are the gold standard for treating moderate to severe pain despite their well-documented adverse effects. Of all prescription medications, opioids are abused most widely, and fatal overdoses have reached epidemic levels. One strategy for improving the margin of safety of...
LitStream

Journal Article

Neuronal nicotinic acetylcholine receptor of the central amygdala modulates the ethanol-induced tolerance to anxiolysis and withdrawal-induced anxiety in male rats

Duratkar, Antariksha; Patel, Richa; Jain, Nishant Sudhir

2024 Behavioural Pharmacology

doi:10.1097/fbp.0000000000000770 pmid:38451025

The nicotine acetylcholinergic receptor (nAchR) in the central nucleus of the amygdala (CeA) is known to modulate anxiety traits as well as ethanol-induced behavioral effects. Therefore, the present study investigated the role of CeA nAChR in the tolerance to ethanol anxiolysis and...

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