1 - 10 of 26 articles
Of 240 patients with Type IIa and IIb hypercholesterolemia recruited in 11 centers, 227 were randomized to double‐blind treatment with either fenofibrate (100 mg three times daily) or matching placebo for 24 weeks. A group of 192 of these patients were studied for a further 24...
The nature of the extracellular matrix may influence the types and amounts of proteoglycans synthesized by arterial smooth muscle cells. To determine if collagen modulates proteoglycan metabolism by these cells, arterial smooth muscle cells derived from aortic explants of the pigtail monkey...
We measured serum lipid and lipoprotein levels in 63 insulin‐dependent diabetic (IDD) patients (32 men, 31 women) and in 63 nondiabetic control subjects (32 men, 31 women) without coronary heart disease (CHD) and in 19 IDD patients (11 men, 8...
Some progeny of baboons (Papiosp.) selectively bred for a high response of serum cholesterol to an atherogenic diet have high serum levels of unusual lipoproteins with flotation rates of F°1,209‐28, intermediate between those of low and high density lipoproteins (HDL)....
Segments of aortocoronary vein grafts from a selective group of 42 patients who underwent a second revascularization procedure or came to autopsy 6 to 12 years after coronary bypass surgery were studied. Complex atheromata often associated with an acute thrombus were present in 71% of the...
We have performed immunocytochemical investigations into the distribution of smooth muscle cells and macrophages in the atherosclerotic lesions of the Watanabe heritable hyperlipidemic (WHHL) and fat‐fed rabbits. We used monoclonal antibodies specific for muscle cells and...
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