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The biosynthesis of extracellular matrix proteins by primary cultures of endothelial cells from human umbilical vein, and by clones from a murlne hemangioendothelioma, was studied and compared to that reported for endothellum cultured from other sources. Umbilical vein endothelial cells secreted...
Lipoproteln compositional studies were carried out in 20 patients with atherosclerotic peripheral vascular disease. Twelve of these patients were normollpldemlc, the other eight, hypertriglycerldemic. Ten normollpldemlc and 10 hypertriglyceridemlc age-matched subjects were used as controls. High...
Plasma concentrations and urinary excretions of various hormones and hormone metabolites were measured In four groups. Group 1 was composed of 13 men with prior myocardial infarction; Group 2 contained 35 clinically normal men; Group 3 consisted of 44 men with normal coronary arteriograms; and...
To determine mechanisms of elevated plasma trlglycerldes (TG) in patients with primary hypertrlglyceridemlas, simultaneous studies were carried out on kinetics of very low density llpoproteln-triglycerides (VLDL-TG) and synthesis of cholesterol and bile acids. Sixteen hypertrlglyceridemlc...
The effect of Interferon administration on the concentration of plasma lipoproteins and on the activity of postheparin plasma llpoproteln llpase and hepatic llpase was studied In six healthy men. Dally Injection of human leukocyte Interferon for 1 week lowered the plasma level of total...
Intermediate density lipoproteins (IDL) (d = 1.006 to 1.019 g/ml) and low density lipoproteins (LDL) (d = 1.019 to 1.063 g/ml) were Isolated from human umbilical cord blood plasma by sequential ultracentrlf ugatlon. The concentration, chemical and apollpoprotein composition, size and size...
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