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The possibility that low high density lipoprotein (HDL) levels may add to the risk of occlusive atherosclerosis in familial hyperchoiesteroiemia (FH) is supported by the frequency and severity of this finding in these patients, particularly homozygotes. To investigate this abnormality in greater...
In the hope of obtaining useful probes to study the structure of human apolipoprotein B (apo B), we characterized monoclonal antibodies against low density lipoprotein (LDL). We examined the distribution of their corresponding antigenic determinants on tryptic fragments of LDL separated by...
Cholesterol-enriched, apolipoprotein E-containing high density lipoproteins (apo E HDLc), which were Isolated from the plasma of cholesterol-fed dogs by using agarose column chromatography or ultracentrlfugatlon, possessed essentially Identical biochemical and metabolic characteristics....
Lipoprotein cholesterol and triglyceride concentrations were compared In diabetic and nondiabetlc Pima Indians, a homogeneous population with a high occurrence of noninsulin-dependent diabetes mellltus. Data were available on 690 subjects with diabetes or impaired glucose tolerance. Total and...
The effect of diet-induced moderate hypercholesterolemia on endothelial healing has been investigated in the rabbit following a narrow superficial injury to aortic endothelium without damage to the media of the vessel. The healing process was compared with that observed in normocholesterolemic...
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