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Introduction: We are using big data mining to develop computational models that predict potential interaction with important biological pathways. Transient receptor potential vanilloid subfamily type 1 (TRPV1) is one of several nociceptors that contribute to sensory irritation. Because sensory...
Introduction: As a chemotherapeutic agent, doxorubicin (DOX) is limited because of systemic toxicities. Repeated treatment with DOX reduces the therapeutic response and increases cellular resistance to the drug. Carotenoids are highly efficient in preventing and treating cancer. Coenzyme Q10...
Introduction: Because of the importance to create in vitro screening tools that better mimic in vivo models, for exposure responses to drugs or toxicants, reproducible and adaptable culture platforms must evolve as approaches to replicate functions that are native to human organ systems. The...
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