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Introduction: The toxicity of inorganic and organic mixtures (CER 16 05 06*), which derive from analytical laboratory waste, being often unstable, represents a relevant issue for their toxicological interactions.Materials and Methods: In compliance with the 3Rs policy adopted by the European...
We reported that blockade of Ca2+ channel increased beating rate on human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) when in hiPSC-CM culture media, but decreased beating rate if extracellular potassium concentration was elevated above certain threshold. When hiPSC-CMs are...
Introduction: The impurities of the air inside the buildings and the resulting adverse health effects have become an increasing problem. Typically indoor air impurities are mixtures of many chemical substances at relative low concentrations. The toxicity of individual substances may be...
Introduction: Idelalisib is a phosphatidylinositol 3-delta kinase inhibitor that has shown good efficacy in treating some hematologic malignancies. Rare, but potentially serious liver toxicity was associated with idelalisib use in clinical trials. The objective of this study was to evaluate the...
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