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AbstractElectronic nicotine delivery systems (ENDS) dispense nicotine by heating a solution (e-liquid) and generating an aerosol that is then inhaled by the user. ENDS have been previously reported by some as less harmful than conventional cigarettes. However, available data regarding the...
AbstractThe Adverse Outcome Pathway (AOP) framework provides a means to outline a knowledge-driven sequence of events from exposure to adverse outcome. As a concept, AOPs have been readily accepted by the toxicology community as a means to organize available mechanistic information linking...
AbstractHypertension is a cardiovascular risk factor that has a profound influence on cardiovascular morbidity and mortality. While good progress has been made in terms of identifying and managing this risk factor for patient care, methods to assess the potential of chemical compounds to induce...
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