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Thirty years of research have established bisphosphonates as the most effective agents for the inhibition of osteoclast-mediated bone resorption, and they play an important role in the management of malignant bone disease. Bisphosphonates have been systematically improved through chemical...
Screening for cancer is a common and expected part of primary care medicine. However, the known effects of lead time, length, and selection bias confound our ability to objectively evaluate screening tests, and often result in an overestimation of the benefits of screening. Because of these...
Children with cancer often cite procedural pain as the most distressing part of their disease. Pharmacologic interventions that decrease the pain and anxiety of invasive procedures have been shown to be beneficial, particularly when these interventions are a routine part of every procedure....
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