1 - 6 of 6 articles
The design of chemotherapy schedules for treatment of malignancies is based on the selection of optimal drug doses with tolerable adverse effects. Interindividual variation in absorption, distribution, metabolism and excretion may exist for a given dose, which depend on both physiological and...
Axillary lymph node dissection (ALND) is typically a standard part of the care of patients with breast cancer. It offers the most precise information about prognosis, controls potential metastatic disease in the axilla, and may provide a small survival advantage. Unfortunately, the procedure is...
Based on the frequent inactivation of the p53 gene product in human malignancy, and its functional involvement in tumor suppression, cell cycle control and apoptosis, p53 was identified as an attractive target for somatic gene therapy strategies in cancer. Several pilot and phase I studies...
Prostate cancer is the second leading cause of cancer death in men. Screening and advances in the treatment of localized disease may help reduce the burden of this disease. Unfortunately, despite progress in these areas, a significant number of men continue to present with advanced disease or to...
For more than a decade, the cisplatin plus doxorubicin and methotrexate plus vinblastine (MVAC) regimen has been the gold standard chemotherapy in bladder cancer, although the toxicity associated with this therapy has hampered its use in many older patients with metastatic disease. In recent...
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Sign Up Log In
To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.