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Biotransformation is one of the processes which influence the bioaccumulation of chemicals. The enzymatic action of metabolism involves two processes, i.e. the binding of the substrate to the enzyme followed by a catalytic reaction, which are described by the Michaelis–Menten constant (Km) and...
In this study, a QSAR model was developed from a data set consisting of 546 organic molecules, to predict acute aquatic toxicity toward Daphnia magna. A modified k-Nearest Neighbour (kNN) strategy was used as the regression method, which provided prediction only for those molecules with an...
The field of toxicity testing is an urgent humanitarian problem, for it regularly involves a finite and large incidence of distress which is often considerable and sometimes acute
The aim of the CADASTER project (CAse Studies on the Development and Application of in SilicoTechniques for Environmental Hazard and Risk Assessment) was to exemplify REACH-related hazard assessments for four classes of chemical compound, namely, polybrominated diphenylethers, per and...
The InterNICHE Policy defines the concept of ‘ethically sourced’ material to encourage replacement and enhance the acquisition of knowledge, skills and attitudes
The new repository will support pharmacology practical teaching by promoting the sharing and re-use of existing pharmacology resources
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