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Advances in Gerontology Volume 2 Issue 4

Subject Areas: Geriatrics and Gerontology; ;
Publisher: SP MAIK Nauka/Interperiodica - Springer Journals
ISSN: 2079-0570
SJR: 9

LitStream

Journal Article

Epigenetic aspects of peptide-mediated regulation of aging

Khavinson, V.; Solov’ev, A.; Zhilinskii, D.; Shataeva, L.; Vanyushin, B.

2012 Advances in Gerontology

doi:10.1134/S2079057012040091

Endogenous peptides in the cyto- and nucleoplasm are formed upon the specific proteasomal degradation of nuclear proteins. These peptides are formed by short blocks of amino-acid residues with charged side groups and therefore a high local concentration of electrostatic charge of either sign is...
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Journal Article

A new class of RNAs and the centrosomal hypothesis of cell aging

Chichinadze, K.; Tkemaladze, J.; Lazarashvili, A.

2012 Advances in Gerontology

doi:10.1134/S2079057012040054

The recent discovery of a new class of RNAs, which are called centrosomal RNAs, in the centrosome is indirect proof of the centrosome hypothesis of cell differentiation and aging, in our opinion. The presence of a reverse transcriptase domain in RNAs of this class and the high specificity of this...
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Journal Article

Characteristics of the aging rate among elderly people in the European North of Russia

Golubeva, E.; Danilova, R.

2012 Advances in Gerontology

doi:10.1134/S2079057012040066

Social factors and the role of the environment, which influence the aging process in the cohort of elderly people in the European North of Russia, are discussed. The indicators of aging of elderly people due to different living conditions with defined risk factors are analyzed. The predominance...
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Journal Article

The effects of immunoglobulins on the clinical and laboratory outlook and morphological changes in patients with mesangial proliferative glomerulonephritis: Age aspects

Sovetkina, N.; Ryabova, T.; Ar’ev, A.; Ovsyannikova, N.

2012 Advances in Gerontology

doi:10.1134/S2079057012040133

The data on 77 mesangial proliferative glomerulonephritis (MPGN) patients with ages of 20–71 years were studied. It was shown that deposits of immunoglobulins in renal tissue affect blood pressure and laboratory parameters of active illness in MPGN patients regardless of age. It was revealed that...
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Journal Article

Cell therapy for age-related intervertebral disc pathologies

Anisimov, S.

2012 Advances in Gerontology

doi:10.1134/S2079057012040029

Any spinal pathology is accompanied by a significant loss in the quality of life and a high disability rate. The rate of occurrence of spinal impairments increases with advancing age. Spinal impairments may be etiologically different and characterized by a wide range of significant and very...
LitStream

Journal Article

Age-related and clinicopathological features of colorectal cancer associated with K-ras gene status

Belyaeva, A.; Yanus, G.; Suspitsyn, E.; Zaitseva, O.; Yatsuk, O.; Moiseenko, A.; Gulyaev, A.; Imyanitov, E.

2012 Advances in Gerontology

doi:10.1134/S2079057012040030

Most human tumors, including colon-cancer tumors, develop in elderly people. One of the significant mutations that cause the development of malignant colon tumors is an activating mutation in the K-ras oncogene. The present study reports the results of a frequency analysis for this mutation in...
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Journal Article

Light pollution increases in the morbidity and mortality rates from different causes in male rats

Bukalev, A.; Vinogradova, I.; Zabezhinskii, M.; Semenchenko, A.; Anisimov, V.

2012 Advances in Gerontology

doi:10.1134/S2079057012040042

This paper investigates the effects of different light regimes (constant light, LL; constant darkness, DD; standard light regime, LD; 12 h light/12 h darkness, natural light of northwest Russia, NL) on the dynamics of lifetime morbidity, spontaneous carcinogenesis, and the incidence of certain...
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Journal Article

Description of the immune system of residents of the Russian Far East during physiological aging

Gvozdenko, T.; Kytikova, O.; Vitkina, T.; Borshchyov, P.

2012 Advances in Gerontology

doi:10.1134/S207905701204008X

Basic parameters of the immune status of relatively healthy people of different ages that live in the monsoon climate in the southern part of the Russian Far East have been considered. This data analysis has shown that the development of an immunodepressive condition in combination with...
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Journal Article

Atherosclerotic affection of the common carotid artery among elderly patients with arterial hypertension: The specifics of peroxide homeostasis

Gorshunova, N.; Ukraintseva, D.

2012 Advances in Gerontology

doi:10.1134/S2079057012040078

To determine the specifics of peroxide homeostasis, which depends on the intensity of atherosclerotic affection of the common carotid artery (CCA), 75 patients aged 60–74 with arterial hypertension (AH) (the average age was 64.62 ± 0.57 years) and 30 nearly healthy elderly people were examined....
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Journal Article

Metabolic syndrome pathophysiology in elderly women with coronary heart disease and arterial hypertension

Ryzhak, G.; Zheltysheva, Zh.

2012 Advances in Gerontology

doi:10.1134/S207905701204011X

This article is dedicated to the study of several metabolic syndrome components in elderly women with coronary heart disease (CHD) and arterial hypertension. The majority of the female patients were found to have visceral obesity, predominantly in a mild form, and dyslipidemia, which was...

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