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Process intensification research is concentrated on the use of the continuous flow microreactor over the conventional batch reactors due to the various advantages that bring this latter in terms of efficient micromixing and enhanced heat and mass transfer in small residence time. The continuous...
Diphenylmethyl (DPM) is a carboxyl protecting group which is often used in the synthesis of β-lactam antibiotics and there are many methods for its removal in industrial production. We have developed a continuous flow method to remove it for β-lactam antibiotics using cresol in microreactor. The...
The selective hydrogenation of halogenated nitroaromatic compounds is of great importance in the fine chemical industry. However, the hydrogenation reactions in commonly utilized batch reactors suffer from the undesired dehalogenation, resulting in higher requirement for subsequent separation...
A reactor has been designed specifically to conduct lithium aluminum hydride reductions in flow. The reactor readily accommodates strong hydrogen gas evolution and allows strict control over the combination of starting material and reductant, the reaction itself, and quenching, all of which are...
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