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Benzocaine (ethyl p-aminobenzoate), ethyl ester of p-aminobenzoic acid, is an anesthetic acting as a blocker of the nerve impulses and reducing the permeability of neuronal membrane to sodium iodide, it has become widespread in the pharmaceutical industry having applications as an anesthetic...
Customized flow equipment was utilized to develop and optimize the halo-amine coupling reaction. In this study, the development work was conducted through the statistical design of experiments (DoE) approach via a 2-factor interaction model. Experiments were conducted in two different reactor...
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