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European Journal of Preventive Cardiology Volume 19 Issue 2_suppl

Subject Areas: Cardiology and Cardiovascular Medicine
Publisher: European Association of Preventive Cardiology - Oxford University Press
ISSN: 2047-4873
SJR: 106

LitStream

Journal Article

Risk-guided therapy: a first step to personalized medicine

Zannad, Faiez; Koenig, Wolfgang

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448991 pmid:22801063

The new European Society of Cardiology (ESC)/European Atherosclerosis Society (EAS) Guidelines for the Management of Dyslipidaemia1 and the updated European Guidelines on Cardiovascular Disease (CVD) Prevention in Clinical Practice2 strongly recommend the use of the systematic coronary risk...
LitStream

Journal Article

The science of risk models

Prieto-Merino, David; Pocock, Stuart J

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448995 pmid:22801064

Abstract An individual’s overall cardiovascular risk should guide appropriate therapy and patient management. Several risk assessment scores are available; however, further development of risk algorithms is necessary to account for changes in available treatments and patient lifestyles, to make...
LitStream

Journal Article

Do novel biomarkers add to existing scores of total cardiovascular risk?

Backer, Guy De; Graham, Ian; Cooney, Marie-Therese

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448988 pmid:22801065

Abstract While cardiovascular disease and certain other conditions are considered to confer a high or very high risk of cardiovascular events, the asymptomatic population can be subdivided in different categories of total CV risk using risk models; this allows the clinician to adapt the intensity...
LitStream

Journal Article

Assessment of subclinical atherosclerosis by carotid intima media thickness: technical issues

Touboul, Pierre-Jean; Grobbee, Diederick E; Ruijter, Hester den

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448990 pmid:22801066

Abstract Carotid intima-media thickness assessed by ultrasonography of carotid arteries is a safe, non-expensive, feasible and accurate method for detecting early signs of atherosclerosis and carotid intima-media thickness and change in carotid intima-media thickness over time reflect...
LitStream

Journal Article

Clinical validation of genetic markers for improved risk estimation

Kessler, Thorsten; Schunkert, Heribert

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448993 pmid:22801067

Abstract Primary prevention is the most effective strategy for reducing the burden of cardiovascular disease; however, predicting cardiovascular risk in the asymptomatic population lacks precision. Traditional methods of estimating risk are based on the presence of certain risk factors, some of...
LitStream

Journal Article

Critical appraisal of trials for validation of ‘risk-guided’ cardiovascular disease prevention therapy

Castro, Almudena; Rosillo, Sandra O; Alonso, Angeles; Pedersen, Terje

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448986 pmid:22801068

Abstract Cardiovascular risk management in the primary prevention population is impeded by the fact that risk scores do not identify properly a low–moderate risk population that could benefit from the use of preventive strategies. Current risk scores are further limited by their complexity and...
LitStream

Journal Article

Implementation, target population, compliance and barriers to risk guided therapy

Tokgozoglu, Lale; Bruckert, Eric

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448989 pmid:22801069

Abstract Early intervention to control cardiovascular disease risk factors can result in significant reductions in cardiovascular disease mortality. However, there is a large gap between risk factor management outlined in clinical guidelines and actual patient care, with preventative medication...
LitStream

Journal Article

A systematic review on the application of cardiovascular risk prediction models in pharmacoeconomics, with a focus on primary prevention

Stevanovic, Jelena; Postma, Maarten J; Pechlivanoglou, Petros

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448994 pmid:22988567

Abstract Background Long-term trials on the effectiveness of pharmacological treatment for primary cardiovascular disease prevention are scant. For that reason risk prediction models are used as a tool to project changes in cardiovascular disease incidence due to changes in risk factor levels...
LitStream

Journal Article

Conclusion

Koenig, Wolfgang; Zannad, Faiez

2012 European Journal of Preventive Cardiology

doi:10.1177/2047487312448992 pmid:22801070

To date, decisions regarding drug therapy for the prevention of cardiovascular disease (CVD) have relied on the assessment of classical risk factors to identify subjects who may be candidates for the initiation and optimization of therapy. Currently, drugs such as statins are mainly prescribed...

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