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Drugs & Therapy Perspectives

Subject Areas: Pharmacology (medical)
Publisher: Springer International Publishing - Springer Journals
ISSN: 1172-0360
SJR: 10

LitStream

Journal Article

Sparsentan in immunoglobulin A nephropathy: a profile of its use

Heo, Young-A; Kang, Connie

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01058-9

Sparsentan (FILSPARI®), an oral, dual endothelin and angiotensin receptor antagonist, is an emerging new treatment option for patients with immunoglobulin A (IgA) nephropathy. Sparsentan received accelerated approval in the USA for the treatment of adults with IgA nephropathy who are at risk of...
LitStream

Journal Article

Treat bipolar depression with atypical antipsychotics and mood stabilisers; new therapies require further study

Fung, Simon

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01054-z

Patients with bipolar disorder frequently suffer from episodes of depression, which is a major cause of morbidity. A range of atypical antipsychotics and mood stabilisers are recommended in guidelines for the treatment of bipolar depression but there is no consensus on which therapies should be...
LitStream

Journal Article

Get on top of gout with a fresh look at treatment options

Fenton, Caroline; Kang, Connie

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01063-y

Managing increasingly prevalent gout, which stems from hyperuricaemia, is not easy. Flare management and long-term serum urate-lowering (ULT) therapy, largely with xanthine oxidase inhibitors (XOIs) or uric acid transporter 1 inhibitors (URAT1Is), are core strategies, but robust comparative...
LitStream

Journal Article

Treating paediatric Crohn’s disease is challenging but new treatments hold promise

Nie, Tina

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01056-x

Paediatric Crohn’s disease is associated with a high disease burden and greater requirement for immunosuppression compared with adult-onset disease. Although anti-tumour necrosis factor therapy can be effective, many patients experience drug failure. Newer biologic and small molecule drugs that...
LitStream

Journal Article

Be aware of the risks of nephrotoxicity when prescribing amoxicillin and third-generation cephalosporins

Zhuang-Yan, Amy

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01060-1

Amoxicillin and third-generation cephalosporins are widely used in the prevention and treatment of established infections. These broad-spectrum antibiotics are mainly excreted via urine and are considered relatively safe. However, several reports have indicated that substantial nephrotoxicity...
LitStream

Journal Article

What is the role of pioglitazone for patients with type 2 diabetes in value-based care settings?

Bush, Andrea; Benny, Tina; Hale, Genevieve; Seamon, Matthew

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01052-1

Type 2 diabetes is a significant burden on the healthcare system with unique challenges in the value-based payment system. Although there are a variety of antidiabetic medications with clinical benefit, access to newer treatments are often limited in value-based settings due to cost,...
LitStream

Journal Article

Correction to: Nadofaragene firadenovec in high-risk Bacillus Calmette Guérin unresponsive non-muscle invasive bladder cancer: a profile of its use

Nie, Tina

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01061-0
LitStream

Journal Article

Correction to: Efanesoctocog alfa in hemophilia A: a profile of its use

Fung, Simon; Blair, Hannah A.

2024 Drugs & Therapy Perspectives

doi:10.1007/s40267-024-01062-z

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