11 - 20 of 27 articles
The dysregulation of transcription factors contributes to the unlimited
proliferation of cancer cells. Transglutaminase 3 (TGM3) has been demonstrated
to play a crucial role in physiology and pathology. However, the potential role
of TGM3 in colorectal cancer...
Subjectivity in oral dysplasia grading has prompted evaluation of molecular‑based
tests to predict malignant transformation. Aneuploidy detected by DNA image‑based
cytometry (ICM) is currently the best predictor but fails to detect certain high
risk lesions. A...
Osteosarcoma is one of the most malignant bone tumors, and its major threats
are aggressive invasion and early tumor metastasis, which result in a poor prognosis
and high mortality. Accumulating evidence indicates that ginsenoside compound
K (CK) has a...
Radioresistance hinders the therapeutic outcomes of radiotherapy in non‑small
cell lung cancer (NSCLC). Although long non‑coding RNAs (lncRNAs) have been demonstrated
to participate in the regulation of multiple cell behaviors, whether they can
Interleukin (IL)‑1β is a member of the IL‑1 family of proteins. IL‑1 receptor
antagonist (IL‑1RA) is an agent that binds to the IL‑1 receptor, preventing IL‑1
from transmitting signals to cells. The present study aimed to identify the role
of the IL‑1β/1RA axis...
Endometrial cancer (EC) is the second leading type of cancer among women,
and its progression is dependent on several factors. The aim of the present study
was to examine the effect of solute carrier organic anion transporter family member
4C1 (SLCO4C1) on...
The biological function of long non‑coding RNA00261 (Linc00261) has been
widely investigated in various types of cancer. The aim of the present study was
to explore the role of Linc00261 in pancreatic cancer (PC). The expression of
Linc00261 in patients with PC...
There are regional and/or ethnic differences in tumorigenic pathways among
several types of cancer, including prostate cancer (PCa). However, information
on genome‑wide gene alterations and the transcriptome is currently only available
for PCa patients from...
Aberrant expression of microRNAs (miRNAs) has been widely reported in many
malignant tumors, and dysregulated miRNAs play an important role in the malignant
progression of tumors. It has been reported that miR‑29c‑3p expression is dysregulated
in tumors and...
Paclitaxel is one of the most effective chemotherapy drugs for breast cancer
worldwide but 20‑30% patients show primary resistance to the drug. Screening and
identification of markers that facilitate effective and rapid prediction of sensitivity
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