1 - 10 of 21 articles
The phosphatidylinositol‑3‑kinase catalytic subunit α (PIK3CA) gene is mutated
in numerous human cancers. This mutation promotes the proliferation of tumor cells;
however, the underlying mechanism is still not clear. In the present study, it
was revealed that...
The platelet isoform of phosphofructokinase (PFKP) is one of the key enzymes
in the glycolytic pathway. PFKP is highly expressed in several
cancers, and it has been reported to be involved in the progression of cancer
cells. However, its oncological...
KIF2A has been shown to be involved in the regulation of AML pathology,
however, the mechanistic role of KIF2A in AML has not been fully identified. The
present study aimed to identify the underlying mechanism of KIF2A regulation of
AML cell function and...
The epithelial‑stromal interaction 1 gene (EPSTI1)
is known to play multiple roles in the malignant progression of breast cancer
and also in some aspects of the immune responses to the tumor. However, the relevance
of the gene in the onset/progression...
The incidence of cancer, which is the second leading cause of mortality
globally, continues to increase, although continued efforts are being made to
identify effective treatments with fewer side‑effects. Previous studies have reported
Micropapillary adenocarcinoma of the lung is a type of cancer associated
with a poor prognosis and is characterized by the presence of tumor cells with
a ring‑like glandular structure floating within alveolar spaces. In the present
study, the association...
The objective of the present study was to clarify the expression characteristics
of long non‑coding RNA (lncRNA) FGD5 antisense RNA 1 (FGD5‑AS1) in pancreatic
cancer, as well as its biological function and underlying mechanism. Reverse transcription‑quantitative...
Colon cancer is one of the most commonly diagnosed malignancies, which begins
as a polyp and grows to become cancer. Diosmin (DS) and naringenin (NR) are naturally
occurring flavonoids that exhibit various pharmacological activities. Although
Neurofibromin 1 (NF1) is a tumor suppressor that has been previously reported
to regulate RAS‑MAPK signaling. The present study investigated the possible relationship
between NF1 expression and anti‑EGFR antibody (cetuximab) sensitivity in colorectal
Promoter methylation represents one of the major epigenetic mechanisms responsible
for the regulation of gene expression. Hypomethylating drugs are currently approved
for the treatment of myelodysplastic syndromes and acute myeloid leukemia, and
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Sign Up Log In
To subscribe to email alerts, please log in first, or sign up for a DeepDyve account if you don’t already have one.
To get new article updates from a journal on your personalized homepage, please log in first, or sign up for a DeepDyve account if you don’t already have one.