1 - 10 of 32 articles
Maintenance of an appropriate oxygen concentration is essential for the
function of the liver. However, in many pathological conditions, and particularly
in the tumor microenvironment, cells and tissues are frequently in a hypoxic state.
In the presence of...
Dogs have been considered as an excellent immunocompetent model for human
melanoma due to the same tumor location and the common clinical and pathological
features with human melanoma. However, the differences in the melanoma transcriptome
between the two...
Emerging evidence has revealed that long noncoding RNAs (lncRNAs) play crucial
roles in the development and progression of tumors. The present study aimed to
examine the roles and illustrate the underlying mechanisms of lncRNA ferritin
heavy chain 1 pseudogene...
Several proteins in the iRhom family function as oncogenic regulators in
certain cancers. However, the function of these proteins in cervical cancer (CC)
is unknown. The relationship of iRhom1 and iRhom2 expression with the clinicopathological
Hepatocellular carcinoma (HCC) is a common disease of the digestive system
with no curative treatments. Long noncoding RNA tyrosine protein kinase transmembrane
receptor 1 antisense RNA 1 (lncRNA ROR1‑AS1) is an lncRNA whose functions have
been predicted in...
Esophageal squamous cell carcinoma (ESCC) is a common type of esophageal
cancer and is prevalent worldwide. Understanding the mechanisms underlying its
formation and the search for more effective therapeutic strategies are critical
due to the occurrence of...
The differential expression of a featured set of genes may serve as a diagnostic
biomarker in hepatocellular carcinoma (HCC) patients. The aim of this study was
to identify prognostic biomarkers for the diagnosis and survival of HCC based
on the analysis of a...
The present study aimed to explore specific molecular targets for the diagnosis
and treatment of non‑small cell lung cancer (NSCLC). The expression profiles of
microRNAs (miRNAs) and mRNAs were downloaded from the GEO (GSE102286 and GSE101929)
Drug resistance to tyrosine kinase inhibitors (TKIs) is currently a clinical
problem in patients with chronic myelogenous leukemia (CML). Homoharringtonine
(HHT) is an approved treatment for adult patients with chronic‑ or accelerated‑phase
CML who are...
Endometrial cancer (EC) is one of the most common malignant gynecological
tumors in women. The main treatments for EC (surgery, chemotherapy and radiation
therapy) produce significant side effects. Thus, it is urgent to identify promising
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