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Radiotherapy (RT) is one of most common treatments for cancer. However,
overcoming the failure and side effects of RT as well as radioresistance, recurrence
and metastasis remains challenging in cancer treatment. Cellular senescence (CS)
is permanent arrested...
The aim of the present study was to investigate the diagnostic and prognostic
value of Wingless‑type MMTV integration site (WNT) gene family expression in patients
with hepatitis B virus (HBV)‑related hepatocellular carcinoma (HCC). The clinical
data of the...
There is recent evidence to indicate the existence of an inverse association
between the incidence of neurological disorders and cancer development. Concurrently,
the transcriptional pathways responsible for the onset of glioblastoma multiforme (GBM)
The integrin α (ITGA) subfamily genes play a fundamental role in various
cancers. However, the potential mechanism and application values of ITGA genes
in colon adenocarcinoma (COAD) remain elusive. The present study investigated
the significance of the...
Hepatocellular carcinoma (HCC) is sexually disparate in humans, with a significantly
increased prevalence in males. The molecular mechanisms by which the inhibition
or development of liver cancer are facilitated require further investigation with
regard to sex...
Breast cancer is the most common type of malignancies in women worldwide,
and genotoxic chemotherapeutic drugs are effective by causing DNA damage in cancer
cells. However, >90% of patients with metastatic cancer are resistant to chemotherapy.
The Forkhead box...
Glioblastoma (GBM) is the most common primary intracranial malignancy. GBM
still exhibits high recurrence and mortality rates even following combined treatment
with surgery, radiotherapy and chemotherapy, Therefore, the identification of
MicroRNAs (miRNAs/miRs) are small non‑coding RNAs that can act as oncogenes
or tumor‑suppressor genes in human cancer. Previous studies have revealed that
abnormal expression of miRNAs is closely associated with tumor cell cycle, differentiation,
Previous researchers have demonstrated that microRNA‑505 (miR‑505) is negatively
correlated with progression in various malignancies. However, the detailed function
and molecular mechanisms of miR‑505 have yet to be completely elucidated in prostate
According to a report of the International Agency for Research on Cancer,
arsenic and inorganic arsenic compounds are classified into Group 1 carcinogens
with regard to human health. Epidemiological studies indicate that arsenic is
one of the main risk factors...
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