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Chromosome Research

Subject Areas: Genetics
Publisher: Springer Netherlands - Springer Journals
ISSN: 0967-3849
SJR: 83

Open Access

Journal Article

Disentangling the roles of aneuploidy, chromosomal instability and tumour heterogeneity in developing resistance to cancer therapies

Andrade, Joana Reis; Gallagher, Annie Dinky; Maharaj, Jovanna; McClelland, Sarah Elizabeth

2023 Chromosome Research

doi:10.1007/s10577-023-09737-5 pmid:37721639

Aneuploidy is defined as the cellular state of having a number of chromosomes that deviates from a multiple of the normal haploid chromosome number of a given organism. Aneuploidy can be present in a static state: Down syndrome individuals stably maintain an extra copy of chromosome 21 in their...

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